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From Biolecture.org
Created page with "<p> </p> <ul> <li>Communication</li> </ul> <p style="margin-left:40px">sorry? / excuse me? / pardon me?</p> <p> </p> <h4>5th sequencing presentation</h4> <ul..."
<p> </p>
<ul>
<li>Communication</li>
</ul>
<p style="margin-left:40px">sorry? / excuse me? / pardon me?</p>
<p> </p>
<h4>5th sequencing presentation</h4>
<ul>
<li>DNA helicase를 이용.</li>
</ul>
<p style="margin-left:40px">purine / pyrimidine : 사이즈의 차이를 인식</p>
<p style="margin-left:40px">AT / GC 염기쌍 : 수소결합 세기 인식</p>
<p style="margin-left:40px">Question : 이게 4세대 sequencing보다 빠를까?</p>
<p style="margin-left:40px"> </p>
<ul>
<li>shadow 의 차이를 이용</li>
</ul>
<p style="margin-left:40px">Question : 3차원 상에 존재하는 base pair를 인식하는게 가능한가?</p>
<p> </p>
<h4>What is genomics?</h4>
<p><img alt="" src="/ckfinder/userfiles/images/genomics.png" style="height:200px; width:300px" /> </p>
<ul>
<li>GEP/T graph</li>
</ul>
<p><img alt="" src="/ckfinder/userfiles/images/GEP%20graph.png" style="height:200px; width:397px" /></p>
<p style="margin-left:40px">⇒ genotype + environment → genotype</p>
<p style="margin-left:40px">⇒ 여러개의 gene이 하나의 phenotype 를 결정하기 때문에 매우 복잡한 연관성을 갖는다</p>
<p style="margin-left:40px"> 따라서 AI를 이용한다! (여러 gene과 environment가 phenotype를 결정하기때문)</p>
<p style="margin-left:40px"> </p>
<ul>
<li>sequencing</li>
</ul>
<p style="margin-left:40px">⇒ calling</p>
<p style="margin-left:40px"> </p>
<ul>
<li>
<h4>Tiger / Whale</h4>
</li>
</ul>
<p style="margin-left: 40px;">⇒ find species / sample</p>
<p style="margin-left:40px">⇒ design : 어떻게 실험을 디자인 할 것인가</p>
<p style="margin-left:40px">1. interesting phenotype</p>
<p style="margin-left:40px">tiger : 육식 / whale : big but no cancer and long life time</p>
<p style="margin-left:40px">⇒ De novo : the new 다시말해 reference가 없음.</p>
<p style="margin-left:40px"> </p>
<p style="margin-left:40px"> </p>
<hr />
<p> </p>
<ul>
<li>Communication</li>
</ul>
<p style="margin-left:40px">sorry? / excuse me? / pardon me?</p>
<p> </p>
<h4>5th sequencing presentation</h4>
<ul>
<li>DNA helicase를 이용.</li>
</ul>
<p style="margin-left:40px">purine / pyrimidine : 사이즈의 차이를 인식</p>
<p style="margin-left:40px">AT / GC 염기쌍 : 수소결합 세기 인식</p>
<p style="margin-left:40px">Question : 이게 4세대 sequencing보다 빠를까?</p>
<p style="margin-left:40px"> </p>
<ul>
<li>shadow 의 차이를 이용</li>
</ul>
<p style="margin-left:40px">Question : 3차원 상에 존재하는 base pair를 인식하는게 가능한가?</p>
<p> </p>
<h4>What is genomics?</h4>
<p><img alt="" src="/ckfinder/userfiles/images/genomics.png" style="height:200px; width:300px" /> </p>
<ul>
<li>GEP/T graph</li>
</ul>
<p><img alt="" src="/ckfinder/userfiles/images/GEP%20graph.png" style="height:200px; width:397px" /></p>
<p style="margin-left:40px">⇒ genotype + environment → genotype</p>
<p style="margin-left:40px">⇒ 여러개의 gene이 하나의 phenotype 를 결정하기 때문에 매우 복잡한 연관성을 갖는다</p>
<p style="margin-left:40px"> 따라서 AI를 이용한다! (여러 gene과 environment가 phenotype를 결정하기때문)</p>
<p style="margin-left:40px"> </p>
<ul>
<li>sequencing</li>
</ul>
<p style="margin-left:40px">⇒ calling</p>
<p style="margin-left:40px"> </p>
<ul>
<li>
<h4>Tiger / Whale</h4>
</li>
</ul>
<p style="margin-left: 40px;">⇒ find species / sample</p>
<p style="margin-left:40px">⇒ design : 어떻게 실험을 디자인 할 것인가</p>
<p style="margin-left:40px">1. interesting phenotype</p>
<p style="margin-left:40px">tiger : 육식 / whale : big but no cancer and long life time</p>
<p style="margin-left:40px">⇒ De novo : the new 다시말해 reference가 없음.</p>
<p style="margin-left:40px"> </p>
<p style="margin-left:40px"> </p>
<hr />
<p> </p>
