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<p><span style="font-size:14px"><span style="font-family:comic sans ms,cursive">1. DNA microarray </span></span></p>
<p><span style="font-size:14px"><span style="font-family:comic sans ms,cursive">A DNA microarray is a collection of microscopic DNA spots attached to a solid surface. Scientists use DNA microarrays to measure the expression levels of large numbers of genes simultaneously or to genotype multiple regions of a genome.</span></span></p>
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<p><img src="https://upload.wikimedia.org/wikipedia/commons/thumb/e/e8/Microarray_exp_horizontal.svg/900px-Microarray_exp_horizontal.svg.png" /></p>
<p><img src="https://upload.wikimedia.org/wikipedia/commons/thumb/a/a8/NA_hybrid.svg/400px-NA_hybrid.svg.png" /></p>
<p><span style="font-size:14px"><span style="font-family:comic sans ms,cursive">2. RNA-seq </span></span></p>
<p><span style="font-size:14px"><span style="font-family:comic sans ms,cursive">RNA-seq, also called whole transcriptome shotgun sequencing (WTSS), usese next-generation sequencing (NGS) to reveal the presence and quantity of RNA in a biological sample at a given moment in time. RNA-seq is used to analyze the continually changing cellular transcriptome. Specifically, RNA-seq facilitates the ability to look at alternative gene spliced transcripts, post-transcriptional modifications, gene fusion, mutasions/SNPs and changes in gene expression. In addition to mRNA transcripts, RNA-seq can look at different populations of RNA to include total RNA, small RNA, such as miRNA, tRNA, and ribosomal profiling. RNA-seq cna also be used to determine exon/intron boundaries and verify or amend previously annotated 5' and 3' gene boundaries.</span></span></p>
<p><img src="https://upload.wikimedia.org/wikipedia/commons/thumb/9/97/Journal.pcbi.1004393.g002.png/1920px-Journal.pcbi.1004393.g002.png" style="height:291px; width:500px" /></p>
