Difference between revisions of "Essay !3 - Genetic Engineering Will Change Everything Forever – CRISPR - Code : KSI0003"
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| − | <p> | + | <p>We've heard a lot about genetic engineering over the past two decades - and, lately there's been even more hype about a new molecular tool called CRISPR, which acts like a cut-and-paste tool for our DNA. But what many of us don't realise is that, after years of talking about it, we're on the verge of a major change for society - one where we can edit genes as easily as we give medication today. What exactly is CRISPR? After all, humans have been genetically engineering other species. Once we discovered DNA, we've been figuring out ways to tinker with this process on the back end, too. Fast forward a few years, and we have genetically engineered mice, genetically engineered humans, and, of course, genetically engineered food.</p> |
| − | <p> | + | <p>But while genetic engineering has played an important role in medicine, the existing techniques available up until now have been expensive, slow, and incredibly complicated.</p> |
| − | <p> | + | <p>Now, that's all changing. Although we're now using CRISPR in humans and other animals, the system was originally found inside bacteria - where it's used as a genetic weapon to stop bacteria being infected by viruses.</p> |
| − | <p> | + | <p>As the video above explains much more beautifully than we can, after a virus has infected a bacteria once, the bacteria keeps a little portion of its DNA locked in a genetic archive called CRISPR. If it ever gets infected again, this viral DNA is turned into RNA, and is fed into a secret weapon called Cas 9 - an enzyme that hunts down any DNA that matches the one in the archive, and then expertly cuts it out of the bacteria. What we will say, without giving too much away, is that, if the idea of designer babies makes you uncomfortable, then get ready, because that's a world we're already living in.</p> |
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<p>Reference</p> | <p>Reference</p> | ||
| − | <p>1. | + | <p>1. https://www.youtube.com/watch?v=jAhjPd4uNFY</p> |
| − | <p>2. | + | <p>2.http://www.sciencealert.com/this-video-explains-perfectly-why-crispr-really-will-change-humanity-forever</p> |
<p>3. Nature Protocols 8, 2281–2308 (2013) doi:10.1038/nprot.2013.143 Published online . 24 October 2013</p> | <p>3. Nature Protocols 8, 2281–2308 (2013) doi:10.1038/nprot.2013.143 Published online . 24 October 2013</p> | ||
| − | <p>4. | + | <p>4. http://www.nature.com/news/crispr-gene-editing-is-just-the-beginning-1.19510</p> |
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<p> </p> | <p> </p> | ||
Latest revision as of 03:22, 3 December 2016
Essay 3 – Genetic Engineering Will Change Everything Forever
– CRISPR -
Sangin Kim
We've heard a lot about genetic engineering over the past two decades - and, lately there's been even more hype about a new molecular tool called CRISPR, which acts like a cut-and-paste tool for our DNA. But what many of us don't realise is that, after years of talking about it, we're on the verge of a major change for society - one where we can edit genes as easily as we give medication today. What exactly is CRISPR? After all, humans have been genetically engineering other species. Once we discovered DNA, we've been figuring out ways to tinker with this process on the back end, too. Fast forward a few years, and we have genetically engineered mice, genetically engineered humans, and, of course, genetically engineered food.
But while genetic engineering has played an important role in medicine, the existing techniques available up until now have been expensive, slow, and incredibly complicated.
Now, that's all changing. Although we're now using CRISPR in humans and other animals, the system was originally found inside bacteria - where it's used as a genetic weapon to stop bacteria being infected by viruses.
As the video above explains much more beautifully than we can, after a virus has infected a bacteria once, the bacteria keeps a little portion of its DNA locked in a genetic archive called CRISPR. If it ever gets infected again, this viral DNA is turned into RNA, and is fed into a secret weapon called Cas 9 - an enzyme that hunts down any DNA that matches the one in the archive, and then expertly cuts it out of the bacteria. What we will say, without giving too much away, is that, if the idea of designer babies makes you uncomfortable, then get ready, because that's a world we're already living in.
Reference
1. https://www.youtube.com/watch?v=jAhjPd4uNFY
3. Nature Protocols 8, 2281–2308 (2013) doi:10.1038/nprot.2013.143 Published online . 24 October 2013
4. http://www.nature.com/news/crispr-gene-editing-is-just-the-beginning-1.19510
