Genomics

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Revision as of 12:59, 29 May 2016 by imported>Jiyoung Oh

<Students are asked to do>

1) Define Genomics your own way after doing research on what genomes are and how we study.

 Genomes - total of genes in cell or species.

 Genomics - The study of sturcures or function of genomes

2) What is the origin of genomics?

genome + omics(=a field of study in biology)

3) History of genomics?

https://en.wikipedia.org/wiki/Genomics (reference)

From the Greek ΓΕΝgen, "gene" (gamma, epsilon, nu, epsilon) meaning "become, create, creation, birth", and subsequent variants: genealogy, genesis, genetics, genic, genomere, genotype, genus etc. While the word genome (from the German Genom, attributed to Hans Winkler) was in use in English as early as 1926, the term genomics was coined by Tom Roderick, a geneticist at the Jackson Laboratory , over beer at a meeting held in Maryland on the mapping of the human genome in 1986.

4) The future of genomics?

The answer is shown in youtube video.

This will be more used in future by comparing genomes between organisms.

5) What is the relationship with other omics?

Omics means the field of study in biology , so genomics, metabolomics and preteomics are all related.

6) How can we engineer genomes?

Genome engineering refers to the strategies and techniques developed in recent years for the targeted, specific modification of the genetic information or genome of living organisms. 

Early approaches to genome engineering involved modifying genetic sequences using only homologous recombination. Using a homologous sequence located on another strand as a model can lead this natural DNA maintenance mechanism to repair a DNA strand. It is possible to induce homologous recombinations between a cellular DNA strand and an exogenous DNA strand inserted in the cell by researchers, using a vector such as the modified genome of a retrovirus. The recombination phenomenon is flexible enough for a certain level of change (addition, suppression or modification of a DNA portion) to be introduced to the targeted homologous area.

homologous recombination, Insertion ,Inactivation, or “knock-out” and Correction aims to remove and replace a defective gene sequence with a functional sequence. 

<Video sources>

https://www.youtube.com/watch?t=20&v=J7AWWpG52zg

After viewing : 

The title is the new age of genomics.

Human genomes is now we're sort of looking on a global scale how life using the bio code software creates what we see around us.

 

<Reference>

http://www.theverge.com/2015/1/6/7501075/bowhead-whale-genome-longevity-first-time-large-whale

The title is  Bowhead whale genome may unlock its longevity secrets.

Scientists have finally sequenced the genome of a large whale and analyzed by comparing genomes resulting in helping humans live longer.

Genomics is perhaps the first such an automated way of pinpointing exact aging associated mutations in such a short time.