Description of Genomics course
Course Description for BME324, Genomics
by Jong Bhak (jongbhak@gmail.com)
Genomics is the new name for genetics that encompasses not only traditional
genetics research and technology topics but also includes information technology, systems biology, high throughput biodata generation, processing, and analyses.
It covers areas such as sequencing, DNA synthesis, and genome writing and editing.
Genomics course requires the students to have been exposed to general
biology, data processing, statistics, mathematics, and computer science.
The genomic research can be largely divided into experimental and informatic
parts. The course will not cover hands-on experiments due to space limitation.
Students who took this subject will be able to understand life in terms of information processing with much knowledge on how to use technologies to solve problems such as curing cancer and aging.
The topics of genomics include:
1. What is life, information, and the universe? (as information processing objects)
2. What is Omics? (as an approach of understanding life)
3. What is 'Big data' in biology?
4. How molecules and cells propagate in the universe?
5. Genome reading and writing
6. Curing Cancer using genomics (Oncomics)
7. Curing Aging using genomics (Geromics)
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Text
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Category
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Book
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Title
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Author
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Arthur M. Lesk,
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ISBN
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Remarks
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Oxford University Press
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Course Reserves Designation
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References
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The Atom of Evolution. Genomics & Informatics, December 2004, 2(4):167-173.
Genomic profile analysis of diffuse-type gastric cancers
Minke whale genome and aquatic adaptation in cetaceans.
Tiger genome and comparative analysis with lion and snow leopard genomes.
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Week
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Contents
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01
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(Course orientation)
What is the Biological Universe?
Mathematics, Physics, Chemistry,
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02
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What is Life on Earth and beyond?
Biochemistry, Biology
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03
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04
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05
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What is Information?
Informatics
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06
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What is Programming?
Perl, Bioperl, Algorithm
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07
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What is Bioinformatics?
Principles of Bioinformatics
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08
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What is Omics?
Various omics
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09
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What is Genomics?
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10
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What is Evolution?
Darwinian evolution
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11
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What is Sequence?
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12
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What is Cancer?
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13
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What is Aging?
Measuring aging
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14
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Research Report presentation
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15
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Research Report presentation
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Grading
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Research report writing and presentation (100%)
Each week, before, class, students are asked to submit research reports on genomics topics. The final grade will be given by the quality of research reports and presentations (in English) The important points of grading are:
1. Being scientific in reasoning and presenting 2. Critical thinking level 3. Being independent in thinking |
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