Chapter !9 - Microarrays and Transcriptomics Code : KSI0018

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<Index of Chpater 9>

Introduction

-Applications of DNA microarrays

Analysis of microarrary data

Expression patterns in different physiological states

-The diauxic shift in Saccharomyces cerevisiae

-Sleep in rats and fruit flies

Expression pattern changes in development

-Variation of expression patterns during the life cycle of Drosophila melanogaster

-Flower formation in roses

Expression patterns in learning and memory : Long-term potentiation

-Conserved clusters of co-expressing genes

Evolutionary changes in expression patterns 

Applications of microarrays in medicine

-Development of antibiotic resistance in bacteria

-Childhood leukaemias

Whole trranscriptome shotgun sequencing : RNA-seq