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Why chromosome shape varies

80 bytes removed, 23:27, 10 December 2017
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<p><strong>Introduction</strong></p>
<p><img alt="" src="/ckfinder/userfiles/images/NHGRI_human_male_karyotype(1).png" style="height:150px; width:191px" />&nbsp;(Figure of Human Chromosomes)</p>
<p>Chromosome is a complex of each DNA molecule and its associated proteins. This is conserved form for prokaryotic and eukaryotic cells, and even for viruses. DNA is packaged into a chromosome to compact the large information and protect DNA from damage. Every cell maintains a characteristic number of chromosomes. One thing I was interested in was the genome size and gene density, because they are&nbsp;closely related to the organism complexity. The other thing was the shape of the packed genome, chromosomes.&nbsp;The chromosomes are all in the same human being, but they all looks different. However, I couldn&#39;t find the reason why their shape is not same to each other. Thus, I tried to figure it out and made a hypothesis. The shape of chromosomes is different because of the evolution.</p>
<p><strong>Result</strong></p>
<p><img alt="" src="/ckfinder/userfiles/images/LIWEEbYBcWWEQCTRKUAAAJaZ.png" style="height:200px; width:586px" />&nbsp;(Overview of Chromosomes of Human GRCh38p.10)</p>
<p>The basic means of my model is just calculating the proportion of length of p-arm in every human chromosomes. Their shapes are different as the location of centromere varies, where the&nbsp;p-arm and q-arm are separated. I found a figure of overview of whole genome as chromosome&nbsp;from Ensembl. It shows the exact location of centromere so it was easy to check where the p-arm is and&nbsp;to analyze the data.</p>
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