imported>Jiyoung Oh |
imported>Jiyoung Oh |
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| | <p>[[Transcriptomics]]</p> | | <p>[[Transcriptomics]]</p> |
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| − | <p><Students are asked to do></p>
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| − | <p>1) Define Genomics your own way after doing research on what genomes are and how we study.</p>
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| − | <p> Genomes - total of genes in cell or species.</p>
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| − | <p> Genomics - The study of sturcures or function of genomes</p>
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| − | <p>2) What is the origin of genomics?</p>
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| − | <p>genome + omics(=a field of study in biology)</p>
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| − | <p>3) History of genomics?</p>
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| − | <p>https://en.wikipedia.org/wiki/Genomics (reference)</p>
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| − | <p>From the Greek ΓΕΝ<em>gen</em>, "gene" (gamma, epsilon, nu, epsilon) meaning "become, create, creation, birth", and subsequent variants: genealogy, genesis, genetics, genic, genomere, genotype, genus etc. While the word <em>genome</em> (from the <a href="https://en.wikipedia.org/wiki/German_language" title="German language">German</a> <em>Genom</em>, attributed to <a href="https://en.wikipedia.org/wiki/Hans_Winkler" title="Hans Winkler">Hans Winkler</a>) was in use in <a href="https://en.wikipedia.org/wiki/English_language" title="English language">English</a> as early as 1926, the term <em>genomics</em> was coined by Tom Roderick, a <a href="https://en.wikipedia.org/wiki/Geneticist" title="Geneticist">geneticist</a> at the <a href="https://en.wikipedia.org/wiki/Jackson_Laboratory" title="Jackson Laboratory">Jackson Laboratory</a> , over beer at a meeting held in <a href="https://en.wikipedia.org/wiki/Maryland" title="Maryland">Maryland</a> on the mapping of the human genome in 1986.</p>
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| − | <p>4) The future of genomics?</p>
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| − | <p>The answer is shown in youtube video.</p>
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| − | <p>This will be more used in future by comparing genomes between organisms.</p>
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| − | <p>5) What is the relationship with other omics?</p>
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| − | <p>Omics means the field of study in biology , so genomics, metabolomics and preteomics are all related.</p>
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| − | <p>6) How can we engineer genomes?</p>
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| − | <p><strong>Genome engineering</strong> refers to the strategies and techniques developed in recent years for the targeted, specific modification of the genetic information or genome of living organisms. </p>
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| − | <p>Early approaches to genome engineering involved modifying genetic sequences using only homologous recombination. Using a homologous sequence located on another strand as a model can lead this natural DNA maintenance mechanism to repair a DNA strand. It is possible to induce homologous recombinations between a cellular DNA strand and an exogenous DNA strand inserted in the cell by researchers, using a vector such as the modified genome of a retrovirus. The recombination phenomenon is flexible enough for a certain level of change (addition, suppression or modification of a DNA portion) to be introduced to the targeted homologous area.</p>
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| − | <p><strong>homologous recombination, Insertion ,Inactivation, or “knock-out” and Correction aims to remove and replace a defective gene sequence with a functional sequence. </strong></p>
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| − | <p><strong><Video sources></strong></p>
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| − | <p>https://www.youtube.com/watch?t=20&v=J7AWWpG52zg</p>
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| − | <p>After viewing : </p>
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| − | <p>The title is the new age of genomics.</p>
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| − | <p>Human genomes is now we're sort of looking on a global scale how life using the bio code software creates what we see around us.</p>
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| | <p> </p> | | <p> </p> |
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| − | <p><strong><Reference></strong></p>
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| − | <p>http://www.theverge.com/2015/1/6/7501075/bowhead-whale-genome-longevity-first-time-large-whale</p>
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| − | <p>The title is Bowhead whale genome may unlock its longevity secrets.</p>
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| − | <p>Scientists have finally sequenced the genome of a large whale and analyzed by comparing genomes resulting in helping humans live longer.</p>
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| − | <p>Genomics is perhaps the first such an automated way of pinpointing exact aging associated mutations in such a short time.</p>
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