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17.06.02

751 bytes added, 20:33, 5 June 2017
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<p><strong>Lecture 4&nbsp;- Transcriptomics</strong></p>
 
<p>* How can we distinguish 5&#39; or 3&#39; in UTR (untranslated region)?<br />
&nbsp;&nbsp;- As using&nbsp;Markov chain model, we can predict 5&#39; and 3&#39; by focusing on their relationship.<br />
&nbsp;&nbsp;- If we have reference, we can also predict 5&#39; of UTR.</p>
 
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<p>** What is Markov chain? **<br />
&nbsp;- Markov chain refers to the sequence of random variables such a process moves through, with the Markov property defining serial dependence only between adjacent preiods.<br />
&nbsp;-&nbsp;It can thus be used for describing systems that follow a chain of linked events, where <u>what happens next depends only on the current state of the system</u>.</p>
 
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<p>* How can we distinguish whether it is UTR or not?</p>