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<p><span id="1434620725139S" style="display: none;">&nbsp;</span></p>
<p>&nbsp;Bio Informatics &nbsp;1st semester</p>
<p>&nbsp;</p>
<p>homework</p>
<p>&nbsp;</p>
<p><span style="font-size: medium;">Bioprogramming 05.07.2015</span></p>
<p>[http://biopedia.org/index.php/BLAST BLAST]</p>
<p>[http://en.wikipedia.org/wiki/SAMtools SAMtools]</p>
<p>[http://genetics.bwh.harvard.edu/pph2/dokuwiki/overview Polyphen-2]</p>
<p>[http://seqanswers.com/wiki/FastQC FastQC]</p>
<p>[http://en.wikipedia.org/wiki/MATLAB MATLAB]</p>
<p>&nbsp;</p>
<p><span style="font-size: medium;">Genomics 05.14.2015</span></p>
<p>[https://en.wikipedia.org/?title=Genomics Genomics]</p>
<p>[https://en.wikipedia.org/wiki/Functional_genomics Functional genomics]</p>
<p>[https://en.wikipedia.org/wiki/Genome_evolution Genome evolution]</p>
<p>[https://en.wikipedia.org/wiki/Structural_genomics Structure genomics]</p>
<p>[https://en.wikipedia.org/wiki/Comparative_genomics Compartive genomics]</p>
<p>&nbsp;</p>
<p><span style="font-size: medium;">Transcriptomics 05.21.2015<br type="_moz" />
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<p>[https://en.wikipedia.org/wiki/RNA-Seq RNA-Seq]</p>
<p>[https://en.wikipedia.org/wiki/List_of_sequence_alignment_software#Short-Read_Sequence_Alignment List of sequence alignment software]</p>
<p>[http://biopedia.org/index.php/De_novo_transcriptome_assembly De novo transcriptome assembly]</p>
<p>[https://en.wikipedia.org/wiki/Salivary_transcriptome Salivary transcriptome]</p>
<p>[https://en.wikipedia.org/wiki/Serial_analysis_of_gene_expression Serial analysis of gene expression]</p>
<p style="margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed;"><span style="font-size: small;"><span style="font-family: '맑은 고딕';">So My</span><span style="font-family: '맑은 고딕'; vertical-align: baseline;"> point of General transcription machinery is about mediator</span><span style="font-family: '맑은 고딕';"> </span></span></p>
<p style="margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed;">&nbsp;</p>
<p>&nbsp;</p>
<p style="margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed;"><span style="font-size: small;"><span style="font-family: '맑은 고딕';">I present</span><span style="font-family: '맑은 고딕'; vertical-align: baseline;"> some talents of Mediator in gene transcription</span></span></p>
<p><span style="font-size: small;">&nbsp;<span style="font-family: '맑은 고딕';">Mediator was Only</span><span style="font-family: '맑은 고딕'; vertical-align: baseline;"> seen as a protein bridge that conveyed regulatory information from enhancers to the promoter</span></span></p>
<p style="margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed;">&nbsp;</p>
<p style="margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed;"><span style="font-size: small;"><span style="font-family: '맑은 고딕';">Indeed,</span><span style="font-family: '맑은 고딕'; vertical-align: baseline;"> recent findings show that Mediator influences nearly all stage of transcription</span><span style="font-family: Arial;">A single activator, is shown recruiting two possible target complexes: the Mediator and RNA polymerase II, as well as the general transcription factor TFIID. Other general transcription factors are either recruited as part of the mediator, Pol II, or TFIID complexes or recruited separately by the activator, or they can bind spontaneously in the presence of the recruited components.</span></span></p>
<p style="margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed;"><span style="font-size: 18pt; font-family: Arial;">&nbsp;<br />
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<p style="margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed;">&nbsp;</p>
<p>what's the real?&nbsp;</p>
<p style="margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed;">&nbsp;</p>
<p style="margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed;"><span style="font-size: small;"><span style="font-family: '맑은 고딕'; vertical-align: baseline;">I recalled this movie and I watched this. Story is that He fall in love with AI</span></span></p>
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<p style="margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed;"><span style="font-size: small;"><span style="font-family: '맑은 고딕'; vertical-align: baseline;">In my opinion, if object has function and people could recognize, it is real</span></span></p>
<p style="margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed;">[http://movie.naver.com/movie/bi/mi/basic.nhn?code=101950 her movie]</p>
<p>&nbsp;</p>
<p><span style="font-size: medium;">proteomics 05.28.2015</span></p>
<p>we just thought the proteins as a nutrient or long chains of amino acid residues. But proteins have complicated features as structures, functions and organisms of our cells etc.</p>
<p>[http://en.wikipedia.org/wiki/Protein_domain Protein domain]</p>
<p>[http://en.wikipedia.org/wiki/Proteome Proteom]</p>
<p>[http://en.wikipedia.org/wiki/Protein_structure Protein structure]</p>
<p>[http://en.wikipedia.org/wiki/Intrinsically_disordered_proteins Disordered protein]</p>
<p>[http://en.wikipedia.org/wiki/Enzyme Enzyme]</p>
<p>&nbsp;</p>
<p><span style="font-size: medium;">Epigenomics 06.042015</span></p>
<p>[https://en.wikipedia.org/wiki/Epigenomics Epigenomics]</p>
<p>[https://en.wikipedia.org/wiki/Biological_clock_(aging) epigenetic clock (aging)]</p>
<p>[https://en.wikipedia.org/wiki/DNA_methylation DNA methylation]</p>
<p>[https://en.wikipedia.org/wiki/Genomic_imprinting Genomic imprinting]</p>
<p>[https://en.wikipedia.org/wiki/Reprogramming Reprogramming]</p>
<p style="margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed;">&nbsp;</p>
<p style="margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed;"><span style="font-size: small;"><span style="font-family: '맑은 고딕'; vertical-align: baseline;">Dawin</span><span style="font-family: '맑은 고딕'; vertical-align: baseline;"> evolution theory is right?</span></span></p>
<p style="margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed;"><span style="font-size: small;"><span style="font-family: '맑은 고딕'; vertical-align: baseline;">I </span><span style="font-family: '맑은 고딕'; vertical-align: baseline;">hasitate</span><span style="font-family: '맑은 고딕'; vertical-align: baseline;"> this and he said Lamarck</span><span style="font-family: '맑은 고딕'; vertical-align: baseline;">ism is right.</span></span></p>
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<p style="margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed;"><span style="font-size: small;"><span style="font-family: '맑은 고딕'; vertical-align: baseline;">I thought whatever right, human research forward the future like aging and many omics. After some year new theory turn to the past theory.</span></span></p>