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<p> </p>
<ol style="list-style-type: decimal; direction: ltr"p> [[Youngjun Bhak]]<li style="font-size: 12pt; font-weight: normal; color: black; font-style: normal"/p> <div style="margin-bottom: 6pt; font-size: 12pt; background: white; font-weight: normal; color: rgb(0,0,0); font-style: normal; margin-top: 4.8pt; line-height: 14.3pt"h2><span style="font-size: 13.5pt; color: black; sans-serif: "> What is transcriptomics?</span></div> </li></olh2>
<p style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt"><span style="font-size: 13.5pt; color: black; sans-serif: ">Thranscriptomics is discipline of biology that study about the set of all RNA moleculs, including mRNA, rRNA, tRNA and non-coding RNA transcribed in one cell or a population of cells</span></p>
<div p style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt"> </divp><ol p style="list-style-type: decimal; direction: ltr"> <li style="font-size: 12pt; font-weight: normal; color: black; font-style: normal"> <div style="margin-bottom: 6pt; font-size: 12pt; background: white; font-weight: normal; color: rgb(0,0,0); font-style: normal; margin-top: 4.8pt0cm 6pt 20pt; line-height: 14.3pt"> </p><h2><span style="font-size: 13.5pt; color: black; sans-serif: ">Relationship between genomics and transcriptomics</span></divh2> </lip style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt"> </olp>
<p style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt"><span style="font-size: 13.5pt; color: black; sans-serif: ">Transcriptomics is expressional genomics. </span></p>
<div p style="background: white; margin: 4.8pt 0cm 6pt 38pt20pt; line-height: 14.3pt"> </divp><ol p style="list-style-type: decimal; direction: ltr"> <li style="font-size: 12pt; font-weight: normal; color: black; font-style: normal"> <div style="margin-bottom: 6pt; font-size: 12pt; background: white; font-weight: normal; color: rgb(0,0,0); font-style: normal; margin-top: 4.8pt0cm 6pt 20pt; line-height: 14.3pt"> </p><h2><span style="font-size: 13.5pt; color: black; sans-serif: ">What are mRNAs?</span></divh2> </lip style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt"> </olp>
<p style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt"><span style="font-size: 13.5pt; color: black; sans-serif: ">mRNA is large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence if the protein products of gene expressing</span></p>
<div style="margin: 0cm 0cm 8pt 40pt"> </div><div p style="background: white; margin: 4.8pt 0cm 6pt 38pt20pt; line-height: 14.3pt"> </divp><ol style="list-style-type: decimal; direction: ltr"> <li style="font-size: 12pt; font-weight: normal; color: black; font-style: normal"> <div p style="margin-bottom: 6pt; font-size: 12pt; background: white; font-weight: normal; color: rgb(0,0,0); font-style: normal; margin-top: 4.8pt0cm 6pt 20pt; line-height: 14.3pt"> </p><h2><span style="font-size: 13.5pt; color: black; sans-serif: ">How to measure RNA expression?</span></div> </li></olh2><p style="background: white; margin: 4.8pt 0cm 6pt 38pt20pt; line-height: 14.3pt"><span style="font-size: 13.5pt; sans-serif: ">RNA-seq method is frequently used for measuring RNA expression.</span></p><div p style="background: white; margin: 4.8pt 0cm 6pt 38pt20pt; line-height: 14.3pt"> </divp><div p style="background: white; margin: 4.8pt 0cm 6pt 38pt20pt; line-height: 14.3pt"> </divp><ol style="list-style-type: decimal; direction: ltr"> <li style="font-size: 12pt; font-weight: normal; color: black; font-style: normal"> <p style="margin-bottom: 6pt; font-size: 12pt; background: white; font-weight: normal; color: rgb(0,0,0); font-style: normal; margin-top: 4.8pt; line-height: 14.3pt"h2><span style="font-size: 13.5pt; color: black; sans-serif: ">Relationship between Transcriptome and Proteome.</span></p> </li></olh2>
<div style="background: white; margin: 4.8pt 0cm 6pt; line-height: 14.3pt; text-indent: 20.25pt"><span style="font-size: 13.5pt; color: black; sans-serif: ">Proteome is expressional Transcriptome. </span></div>
<div style="background: white; margin: 4.8pt 0cm 0cm 8pt 40pt6pt; line-height: 14.3pt; text-indent: 20.25pt"> </div><div style="background: white; margin: 4.8pt 0cm 6pt 38pt; line-height: 14.3pt; text-indent: 20.25pt"> </div><ol style="list-style-type: decimal; direction: ltr"h2> <li span style="font-size: 12pt; font-weight: normal13.5pt; color: black; fontsans-styleserif: normal">What is a UTR?</span></h2> <div style="margin-bottom: 6pt; font-size: 12pt; background: white; font-weight: normal; color: rgb(0,0,0); font-style: normal; margin-top: 4.8pt0cm 6pt; line-height: 14.3pt"><span style="font; text-sizeindent: 1320.5pt; color: black; sans-serif: 25pt">What is a UTR?</span> </div> </li></ol><p style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt"><span style="font-size: 13.5pt; background: white; sans-serif: ">Untranslated region </span><span style="font-size: 13.5pt; background: white; sans-serif: ">(or UTR) refers to either of two sections, one on each side of a </span><a title="Coding sequence" href="http://en.wikipedia.org/wiki/Coding_sequence"><span style="font-size: 13.5pt; text-decoration: none; background: white; color: windowtext; text-underline: none; sans-serif: ">coding sequence</span> <span style="font-size: 13.5pt; background: white; sans-serif: ">on a strand of </span></a><a title="MRNA" href="http://en.wikipedia.org/wiki/MRNA"><span style="font-size: 13.5pt; text-decoration: none; background: white; color: windowtext; text-underline: none; sans-serif: ">mRNA</span><span style="font-size: 13.5pt; background: white; sans-serif: ">. If it is found on the 5' side, it is called the </span></a><a title="Five prime untranslated region" href="http://en.wikipedia.org/wiki/Five_prime_untranslated_region"><span style="font-size: 13.5pt; text-decoration: none; background: white; color: windowtext; text-underline: none; sans-serif: ">5' UTR</span> <span style="font-size: 13.5pt; background: white; sans-serif: ">(or leader sequence), or if it is found on the 3' side, it is called the </span></a><a title="Three prime untranslated region" href="http://en.wikipedia.org/wiki/Three_prime_untranslated_region"><span style="font-size: 13.5pt; text-decoration: none; background: white; color: windowtext; text-underline: none; sans-serif: ">3' UTR</span> <span style="font-size: 13.5pt; background: white; sans-serif: ">(or trailer sequence).</span></a></a></a></a></p><div p style="background: white; margin: 4.8pt 0cm 6pt 38pt20pt; line-height: 14.3pt"> </divp><ol style="list-style-type: decimal; direction: ltr"> <li p style="font-size: 12pt; font-weight: normal; color: black; font-style: normal"> <div style="margin-bottom: 6pt; font-size: 12pt; background: white; font-weight: normal; color: rgb(0,0,0); font-style: normal; margin-top: 4.8pt0cm 6pt 20pt; line-height: 14.3pt"> </p><h2><span style="font-size: 13.5pt; color: black; sans-serif: ">What is ncRNA ?</span></divh2> </lip style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt"> </olp><div style="margin: 0cm 0cm 8pt 15pt"><span style="font-size: 13.5pt; background: white; line-height: 107%; sans-serif: ">A non-coding RNA (ncRNA) is a functional </span><a title="RNA" href="http://en.wikipedia.org/wiki/RNA"u><span style="font-size: 13.5pt; text-decoration: none; background: white; color: windowtext; line-height: 107%; text-underline: none; sans-serif: ">RNAMolecule that is not<font color="#0066cc"> </spanfont> </span style="font-size: 13.5pt; background: white; line-height: 107%; sans-serif: ">molecule that is not </spanu><a title="Translation (genetics)" href="http://en.wikipedia.org/wiki/Translation_(genetics)"><u><span style="font-size: 13.5pt; text-decoration: none; background: white; color: windowtext; line-height: 107%; text-underline: none; sans-serif: ">translated</span><span style="font-size: 13.5pt; background: white; line-height: 107%; sans-serif: "> into a </span></u></a><a title="Protein" href="http://en.wikipedia.org/wiki/Protein"><u><span style="font-size: 13.5pt; text-decoration: none; background: white; color: windowtext; line-height: 107%; text-underline: none; sans-serif: ">protein</span></a></au></a></div>
<div style="background: white; margin: 4.8pt 0cm 6pt 38pt; line-height: 14.3pt"> </div>
<div style="background: white; margin: 4.8pt 0cm 6pt 38pt; line-height: 14.3pt"> </div>
<p style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt"><span style="font-size: 13.5pt; color: black; sans-serif: ">Poly A is long tail sequence of adenine nucleotides add it the 3’end of the pre-mRNA. This promotes export from the nucleus and translation, and protects the mRNA from degradation</span></p>
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