<pdiv>&nbsp;</p><h1 class="article-heading" span style="margin: 0px 0px 20px; padding: 0px; font-size: 28.799999237060547px; fontx-weight: normallarge; color: rgb(34, 34, 34); line-height: 1.173">The tiger genome and comparative analysis with lion and snow leopard genomes</span></div><div>&nbsp; font-family: arial</div><div>Yun Sung Cho, helveticaLi Hu, 'ＭＳ Ｐゴシック'Haolong Hou, 'ＭＳ ゴシック'Hang Lee, Jiaohui Xu, Soowhan Kwon, Sukhun Oh, Hak-Min Kim, OsakaSungwoong Jho, 'MS PGothic'Sangsoo Kim, sansYoung-serif;">The tiger genome and comparative analysis with lion and snow leopard genomes</h1><ul class="authors citationAh Shin, Byung Chul Kim, Hyunmin Kim, Chang-authors" style="margin: 0px 0px 10px; padding: 0px; fontuk Kim, Shu-weight: bold; color: rgb(51Jin Luo, 51Warren E. Johnson, 51); fontKlaus-family: arialPeter Koepfli, helveticaAnne Schmidt-K&uuml;ntzel, 'ＭＳ Ｐゴシック'Jason A. Turner, 'ＭＳ ゴシック'Laurie Marker, Cindy Harper, OsakaSusan M. Miller, 'MS PGothic'Wilhelm Jacobs, sans-serif; font-size: 14Laura D.399999618530273px; lineBertola, Tae Hyung Kim, Sunghoon Lee, Qian Zhou, Hyun-height: 23.912500381469727px;"> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-1" class="name" style="color: rgb(92Ju Jung, Xiao Xu, Priyvrat Gadhvi, Pengwei Xu, Yingqi Xiong, Yadan Luo, Shengkai Pan, Caiyun Gou, Xiuhui Chu, Jilin Zhang, Sanyang Liu, Jing He, Ying Chen, Linfeng Yang, Yulan Yang, 121Jiaju He, 150); text-decoration: none;"><span class="fn">Yun Sung Cho</span></a><span class="comma">Sha Liu, Junyi Wang, Chul Hong Kim,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; listHwanjong Kwak, Jong-Soo Kim, Seungwoo Hwang, Junsu Ko, Chang-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-2" class="name" style="color: rgb(92Bae Kim, Sangtae Kim, Damdin Bayarlkhagva, 121Woon Kee Paek, 150); textSeong-decoration: noneJin Kim, Stephen J. O&rsquo;Brien, Jun Wang &amp;"[[Jong Bhak]]</div><span class="fn"div>Li Hu&nbsp;</spandiv></adiv><span class="comma"[[AffiliationsContributionsCorresponding authors]]</div>,</spandiv>&nbsp;</lidiv> <li class="vcard" style="margindiv>Nature Communications 4, Article number: 0px; padding2433 doi: 0px; list-style: none; display: inline;"10.1038/ncomms3433</div><a href="http://www.nature.com/ncomms/div>Received 02 May 2013 Accepted 13 August 2013 Published 17 September 2013</130917div><div>&nbsp;</ncomms3433div><div>&nbsp;</full/ncomms3433.html#auth-3" class="name" div><div><b><span style="color: rgb(92, 121, 150); textfont-decorationsize: nonelarge;">Abstract</span class="fn">Haolong Hou</spanb></adiv><span class="comma"div>,</span></li> <li class="vcard" style="margincolor: 0pxrgb(51, 51, 51); padding: 0px; listfont-stylefamily: none; display: inline;"><a href="httparial, helvetica, 'ＭＳ Ｐゴシック', 'ＭＳ ゴシック', Osaka, 'MS PGothic', sans-serif; font-size://www14.nature399999618530273px; line-height: 23.com912500381469727px;">Tigers and their close relatives (</ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-4" class="name" span><i style="color: rgb(9251, 12151, 15051); textfont-decorationfamily: none;"><span class="fnarial, helvetica, 'ＭＳ Ｐゴシック', 'ＭＳ ゴシック', Osaka, 'MS PGothic', sans-serif; font-size: 14.399999618530273px; line-height: 23.912500381469727px;">Hang LeePanthera</spani></a><span class="comma">,</span></li> <li class="vcard" style="margincolor: 0pxrgb(51, 51, 51); padding: 0px; listfont-stylefamily: none; display: inlinearial, helvetica, 'ＭＳ Ｐゴシック', 'ＭＳ ゴシック', Osaka, 'MS PGothic', sans-serif;"><a href="httpfont-size://www14.nature399999618530273px; line-height: 23.com912500381469727px;">) are some of the world&rsquo;s most endangered species. &nbsp;Here we report the&nbsp;</ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-5" class="name" span><i style="color: rgb(9251, 12151, 15051); textfont-decorationfamily: none;arial, helvetica, 'ＭＳ Ｐゴシック', 'ＭＳ ゴシック', Osaka, 'MS PGothic', sans-serif; font-size: 14.399999618530273px; line-height: 23.912500381469727px;"><span class="fn">Jiaohui Xu</span>de novo</a><span class="comma"i>,</span></li> <li class="vcard" style="margincolor: 0pxrgb(51, 51, 51); paddingfont-family: 0pxarial, helvetica, 'ＭＳ Ｐゴシック', 'ＭＳ ゴシック', Osaka, 'MS PGothic', sans-serif; listfont-stylesize: none14.399999618530273px; displayline-height: inline23.912500381469727px;"><&nbsp;assembly of an Amur tiger whole-genome sequence as well as the genomic sequences of a href="http://wwwwhite Bengal tiger, African lion, white African lion and snow leopard.nature&nbsp;Through comparative genetic analyses of these genomes, we find genetic signatures that may reflect molecular adaptations consistent with the big cats&rsquo; hypercarnivorous diet and muscle strength.com&nbsp;We report a snow leopard-specific genetic determinant in&nbsp;</ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-6" class="name" span><i style="color: rgb(9251, 12151, 15051); textfont-decorationfamily: none;"><span class="fn">Soowhan Kwon</spanarial, helvetica, 'ＭＳ Ｐゴシック', 'ＭＳ ゴシック', Osaka, 'MS PGothic', sans-serif; font-size: 14.399999618530273px; line-height: 23.912500381469727px;">EGLN1</ai><span classstyle="comma">color: rgb(51, 51,</span></li> <li class="vcard" style="margin: 0px51); padding: 0px; listfont-stylefamily: none; display: inline;"><a href="httparial, helvetica, 'ＭＳ Ｐゴシック', 'ＭＳ ゴシック', Osaka, 'MS PGothic', sans-serif; font-size://www14.nature399999618530273px; line-height: 23.com912500381469727px;">&nbsp;(Met39&gt;Lys39), which is likely to be associated with adaptation to high altitude. &nbsp;We also detect a&nbsp;</ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-7" class="name" span><i style="color: rgb(9251, 12151, 15051); textfont-decorationfamily: nonearial, helvetica, 'ＭＳ Ｐゴシック', 'ＭＳ ゴシック', Osaka, 'MS PGothic', sans-serif;"><span class="fn">Sukhun Oh</spanfont-size: 14.399999618530273px; line-height: 23.912500381469727px;">TYR</a><span class="comma"i>,</span></li> <li class="vcard" style="margincolor: 0px; padding: 0pxrgb(51, 51, 51); listfont-stylefamily: nonearial, helvetica, 'ＭＳ Ｐゴシック', 'ＭＳ ゴシック', Osaka, 'MS PGothic', sans-serif; displayfont-size: inline14.399999618530273px; line-height: 23.912500381469727px;"><a href="http://www260G&gt;A mutation likely responsible for the white lion coat colour. &nbsp;Tiger and cat genomes show similar repeat composition and an appreciably conserved synteny.nature&nbsp;Genomic data from the five big cats provide an invaluable resource for resolving easily identifiable phenotypes evident in very close, but distinct, species.com</ncommsspan></2013/130917/ncomms3433div><div>&nbsp;</full/ncomms3433.html#auth-8" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"div><span class="fn"div>Hak-Min Kim</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none&nbsp; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-9" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Sungwoong Jho</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-10" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Sangsoo Kim</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-11" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Young-Ah Shin</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-12" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Byung Chul Kim</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-13" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Hyunmin Kim</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-14" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Chang-uk Kim</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-15" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Shu-Jin Luo</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-16" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Warren E. Johnson</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-17" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Klaus-Peter Koepfli</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-18" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Anne Schmidt-K&uuml;ntzel</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-19" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Jason A. Turner</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-20" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Laurie Marker</span></a><span class="comma" style="display: inline;">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-21" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Cindy Harper</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-22" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Susan M. Miller</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-23" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Wilhelm Jacobs</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-24" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Laura D. Bertola</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-25" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Tae Hyung Kim</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-26" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Sunghoon Lee</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-27" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Qian Zhou</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-28" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Hyun-Ju Jung</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-29" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Xiao Xu</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-30" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Priyvrat Gadhvi</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-31" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Pengwei Xu</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-32" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Yingqi Xiong</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-33" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Yadan Luo</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-34" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Shengkai Pan</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-35" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Caiyun Gou</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-36" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Xiuhui Chu</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-37" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Jilin Zhang</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-38" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Sanyang Liu</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-39" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Jing He</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-40" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Ying Chen</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-41" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Linfeng Yang</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-42" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Yulan Yang</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-43" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Jiaju He</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-44" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Sha Liu</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-45" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Junyi Wang</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-46" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Chul Hong Kim</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-47" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Hwanjong Kwak</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-48" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Jong-Soo Kim</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-49" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Seungwoo Hwang</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-50" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Junsu Ko</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-51" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Chang-Bae Kim</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-52" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Sangtae Kim</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-53" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Damdin Bayarlkhagva</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-54" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Woon Kee Paek</span></a><span class="comma">,</span></li> <li class="vcard" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-55" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Seong-Jin Kim</span></a><span class="comma">,</span></li> <li class="vcard c1" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-56" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Stephen J. O&rsquo;Brien</span></a><span class="comma">,</span></li> <li class="vcard c1 no-comma" style="margin: 0px; padding: 0px; list-style: none; display: inline;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#auth-57" class="name" style="color: rgb(92, 121, 150); text-decoration: none;"><span class="fn">Jun Wang</span></a></li> <li class="vcard last-author c1 no-comma" style="margin: 0px; padding: 0px; list-style: none; display: inline;">&amp;&nbsp;<span style="color: rgb(0, 0, 0);">[[Jong Bhak]]</span></span></li></ul><ul id="author-links" class="cleared" style="margin: 0px 0px 20px; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, 'ＭＳ Ｐゴシック', 'ＭＳ ゴシック', Osaka, 'MS PGothic', sans-serif; font-size: 14.399999618530273px; line-height: 23.912500381469727px;"> <li class="first" style="margin: 0px; padding: 0px 0.5em 0px 0px; list-style: none; float: left; background-image: none; background-attachment: scroll; background-position: 0px 0.6ex; background-repeat: no-repeat no-repeat;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#affil-auth" style="color: rgb(92, 121, 150); text-decoration: none; font-weight: bold;">Affiliations</a></li> <li style="margin: 0px; padding: 0px 0.5em; list-style: none; float: left; background-image: url(http://www.nature.com/view/images/bg_pipe.gif); background-attachment: scroll; background-position: 0px 0.6ex; background-repeat: no-repeat no-repeat;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#contrib-auth" style="color: rgb(92, 121, 150); text-decoration: none; font-weight: bold;">Contributions</a></li> <li style="margin: 0px; padding: 0px 0.5em; list-style: none; float: left; background-image: url(http://www.nature.com/view/images/bg_pipe.gif); background-attachment: scroll; background-position: 0px 0.6ex; background-repeat: no-repeat no-repeat;"><a href="http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html#corres-auth" style="color: rgb(92, 121, 150); text-decoration: none; font-weight: bold;">Corresponding authors</a></li></ul><dl class="citation" style="margin: 0px; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, 'ＭＳ Ｐゴシック', 'ＭＳ ゴシック', Osaka, 'MS PGothic', sans-serif; font-size: 14.399999618530273px; line-height: 23.912500381469727px;"><dd class="journal-title" style="margin: 0px; padding: 0px 3px 0px 0px; font-style: italic; text-transform: capitalize; display: inline;">Nature Communications</dd>&nbsp;<dd class="volume" style="margin: 0px; padding: 0px 3px 0px 0px; font-weight: bold; display: inline;">4<span style="font-weight: normal;">,</span></dd>&nbsp;<dt class="seq" style="margin: 0px; padding: 0px; display: inline;">Article number:</dt>&nbsp;<dd class="page" style="margin: 0px; padding: 0px 3px 0px 0px; display: inline;">2433</dd>&nbsp;<dd class="doi" style="margin: 0px 0px 0px 4px; padding: 0px 3px 0px 10px; display: inline; background-image: url(http://www.nature.com/view/images/bg_pipe.gif); background-position: 0px 0.4ex; background-repeat: no-repeat no-repeat;">doi:10.1038/ncomms3433</dd></dl><dl class="citation dates" style="margin: 0px; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, 'ＭＳ Ｐゴシック', 'ＭＳ ゴシック', Osaka, 'MS PGothic', sans-serif; font-size: 14.399999618530273px; line-height: 23.912500381469727px;"><dt class="received first" style="margin: 0px; padding: 0px 3px 0px 0px; display: inline; background-image: none !important;">Received</dt>&nbsp;<dd style="margin: 0px; padding: 0px 3px 0px 0px; display: inline;"><time datetime="2013-05-02">02 May 2013&nbsp;</time></dd><dt class="accepted" style="margin: 0px; padding: 0px 3px 0px 8px; display: inline; background-image: url(http://www.nature.com/view/images/bg_pipe.gif); background-position: 0px 0.4ex; background-repeat: no-repeat no-repeat;">Accepted</dt>&nbsp;<dd style="margin: 0px; padding: 0px 3px 0px 0px; display: inline;"><time datetime="2013-08-13">13 August 2013&nbsp;</time></dd><dt class="published-online" style="margin: 0px; padding: 0px 3px 0px 8px; display: inline; background-image: url(http://www.nature.com/view/images/bg_pipe.gif); background-position: 0px 0.4ex; background-repeat: no-repeat no-repeat;">Published</dt>&nbsp;<dd style="margin: 0px; padding: 0px 3px 0px 0px; display: inline;"><time datetime="2013-09-17">17 September 2013</time></dd></dl><dl class="citation dates" style="margin: 0px; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, 'ＭＳ Ｐゴシック', 'ＭＳ ゴシック', Osaka, 'MS PGothic', sans-serif; font-size: 14.399999618530273px; line-height: 23.912500381469727px;"><br type="_moz" </div></dldiv><dl class="citation dates" style="margin: 0px; padding: 0px; color: rgb(51, 51, 51); font-family: arial, helvetica, 'ＭＳ Ｐゴシック', 'ＭＳ ゴシック', Osaka, 'MS PGothic', sans-serif; font-size: 14.399999618530273px; line-height: 23.912500381469727px&nbsp;"><br type="_moz" /></dldiv>