<p>&nbsp;</p>

<p><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Javier Prado-Martinez</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins1" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">1</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Irene Hernando-Herraez</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins1" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">1</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Belen Lorente-Galdos</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins1" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">1</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Marc Dabad</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins1" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">1</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Oscar Ramirez</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins1" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">1</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Carlos Baeza-Delgado</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins2" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">2</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Carlos Morcillo-Suarez</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins1" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">1</a></sup><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins3" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">3</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Can Alkan</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins4" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">4</a></sup><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins5" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">5</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Fereydoun Hormozdiari</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins4" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">4</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Emanuele Raineri</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins6" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">6</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Jordi Estell&eacute;</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins6" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">6</a></sup><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins7" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">7</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Marcos Fernandez-Callejo</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins1" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">1</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">M&ograve;nica Valles</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins1" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">1</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Lars Ritscher</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins8" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">8</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Torsten Sch&ouml;neberg</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins8" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">8</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Elisa de la Calle-Mustienes</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins9" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">9</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">S&ograve;nia Casillas</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins10" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">10</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Raquel Rubio-Acero</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins10" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">10</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Marta Mel&eacute;</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins1" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">1</a></sup><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins11" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">11</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Johannes Engelken</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins1" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">1</a></sup><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins12" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">12</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Mario Caceres</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins10" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">10</a></sup><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins13" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">13</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Jose Luis Gomez-Skarmeta</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins9" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">9</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Marta Gut</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins6" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">6</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Jaume Bertranpetit</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins1" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">1</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Ivo G Gut</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins6" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">6</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Teresa Abello</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins14" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">14</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Evan E Eichler</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins15" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">15</a></sup><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins4" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">4</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Ismael Mingarro</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins2" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">2</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Carles Lalueza-Fox</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins1" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">1</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">,&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Arcadi Navarro</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins1" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">1</a></sup><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins13" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">13</a></sup><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins16" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">16</a></sup><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins3" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">3</a></sup><span style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em;">&nbsp;and&nbsp;</span><strong style="font-family: inherit; font-size: 1em; font-style: inherit; line-height: 1.6em; padding: 0px; margin: 0px; border: 0px; outline: 0px; vertical-align: baseline;">Tomas Marques-Bonet</strong><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins1" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">1</a></sup><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;"><a href="http://www.biomedcentral.com/1471-2164/14/363/#ins13" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-size: 8.800000190734863px; font-family: inherit; vertical-align: baseline; color: rgb(38, 115, 186);">13</a></sup><sup style="font-family: inherit; font-style: inherit; line-height: 1.6em; padding: 0px 0.2em 0px 0px; margin: 0px;">*</sup></p>

<p><section style="padding: 0px; margin: 0px; font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 11.199999809265137px; line-height: 12.800000190734863px;">

<div class="collapsible-content" style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-style: inherit; font-family: inherit; vertical-align: baseline;">

<p style="padding: 0px; margin: 0px 0px 1em; border: 0px; outline: 0px; font-style: inherit; font-family: inherit; vertical-align: baseline; overflow: visible; clear: both; line-height: 17.600000381469727px;">The only known albino gorilla, named&nbsp;<em style="padding: 0px; margin: 0px; border: 0px; outline: 0px; font-family: inherit; vertical-align: baseline;">Snowflake</em>, was a male wild born individual from Equatorial Guinea who lived at the Barcelona Zoo for almost 40 years. He was diagnosed with non-syndromic oculocutaneous albinism, i.e. white hair, light eyes, pink skin, photophobia and reduced visual acuity. Despite previous efforts to explain the genetic cause, this is still unknown. Here, we study the genetic cause of his albinism and making use of whole genome sequencing data we find a higher inbreeding coefficient compared to other gorillas.</p>

<p><span style="font-size: large;">Results</span></p>

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</section></p>

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