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Resistance to reactive oxygen species in cetaceans

Reactive Oxygen Species(ROS)

Antioxidant

Evolved KEGG pathway in cetaceans

 

References: 

Hyung.S.Y., Yun.S.C., Xuanmin.G., Sung.G.K., Jae.Y.J., Sun.S.C., … Jung.H.L. Minke Whale genome and aquatic adaptation in cetaceans. Nature Genetics 46, 88-92 (2013)

http://mpmp.huji.ac.il/maps/gluth_met.html - Glutathione metabolism

James P. Kehrer and Lars-Oliver Klotz. Free radicals and related reactive species as mediators of tissue injury and disease: implications for Health. CRITICAL REVIEWS IN TOXICOLOGY (2015)

Chad Kerksick and Darryn Willoughby. The Antioxidant Role of Glutathione and N-AcetylCysteine Supplements and Exercise-Induced Oxidative Stress. J Int Soc Sports Nutr. 2(2): 38–44 (2005)

Christine H. Foyer, Nadège Souriau, Sophie Perret, Maud Lelandais, Karl-Josef Kunert, Christophe Pruvost, and Lise Jouanin. Overexpression of Glutathione Reductase but Not Glutathione Synthetase Leads to lncreases in Antioxidant Capacity and Resistance to Photoinhibition in Poplar Trees. Plant Physiol. 109: 1047-1057 (1995)

https://www.youtube.com/watch?v=gUUsTbeu4LE - It is good to watch to understand ROS

https://www.youtube.com/watch?v=U-3EJlX0v_c - Good to watch to get knowledge of glutathione as antioxidant

https://en.wikipedia.org