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<p style="text-align: center;"><span style="font-size:26px">Essay 6 - About the Blast and BLAT.</span></p>
<p>In <a href="https://en.wikipedia.org/wiki/Bioinformatics" title="Bioinformatics">bioinformatics</a>, <strong>BLAST</strong> for <strong>B</strong>asic <strong>L</strong>ocal <strong>A</strong>lignment <strong>S</strong>earch <strong>T</strong>ool is an <a href="https://en.wikipedia.org/wiki/Algorithm" title="Algorithm">algorithm</a> for comparing <a href="https://en.wikipedia.org/wiki/Primary_structure" title="Primary structure">primary</a> biological sequence information, such as the <a href="https://en.wikipedia.org/wiki/Amino_acid" title="Amino acid">amino-acid</a> sequences of <a href="https://en.wikipedia.org/wiki/Protein" title="Protein">proteins</a> or the <a href="https://en.wikipedia.org/wiki/Nucleotide" title="Nucleotide">nucleotides</a> of <a href="https://en.wikipedia.org/wiki/DNA_sequence" title="DNA sequence">DNA sequences</a>. A BLAST search enables a researcher to compare a query sequence with a library or <a href="https://en.wikipedia.org/wiki/Database" title="Database">database</a> of sequences, and identify library sequences that resemble the query sequence above a certain threshold.</p>
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<p><img alt="" src="/ckfinder/userfiles/images/dd(1).PNG" style="height:768px; width:1366px" /><img alt="" src="/ckfinder/userfiles/images/d.PNG" style="height:768px; width:1366px" /><img alt="" src="/ckfinder/userfiles/images/sd.PNG" style="height:768px; width:1366px" /></p> <p>Like this way, we can find the zebrafish's apex1 gene gRNA target site and which exon was targeted. </p>
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