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Essay !1 - Genomics & Omics - Code : KSI0001

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<p style="text-align:center"><strong><span style="font-size:24px">&lt; Genomics Essay 1 &gt;</span></strong></p>
 
<p style="text-align:right"><strong><span style="font-size:12px">Sangin Kim</span></strong></p>
 
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<p><strong>&nbsp;Genomics</strong>&nbsp;refers to the study of the genome&nbsp;in contrast to genetics which refers to the study of genes and their roles in inheritance.&nbsp;Genomics can be considered a discipline in genetics. It applies recombinant DNA, DNA sequencing&nbsp;methods, and bioinformatics to&nbsp;sequence, assemble, and analyze the function and structure of genomes.&nbsp;The field includes efforts to determine the entire DNA sequence&nbsp;of organisms and fine-scale genetic mapping. The field also includes studies of intragenomic phenomena such as heterosis, epistasis, pleiotropy or other interactions between loci and alleles within the genome. It is the new science that deals with the discovery and noting of all the sequences in the entire genome of a particular organism. The genome can be defined as the complete set of genes inside a cell. Genomics, is, therefore, the study of the genetic make-up of organisms.</p> <p>&nbsp;Determining the genomic sequence, however, is only the beginning of genomics. Once this is done, the genomic sequence is used to study the function of the numerous genes&nbsp;to compare the genes in one organism with those of another (comparative genomics), or to generate the 3Essay 1 -D structure of one or more proteins from each protein family, thus offering clues to their function. In crop agriculture, the main purpose of the application of genomics is to gain a better understanding of the whole genome of plants. Agronomically important genes may be identified and targeted to produce more nutritious and safe food while at the same time preserving the environment. Genomics is an entry point for looking at the other &lsquoamp;omics&rsquo; sciences.</p> <p>&nbsp;The information in the genes of an organism, its genotype, is largely responsible for the final physical makeup of the organism, referred to as the &ldquo;phenotype&rdquo;. However, the environment also has some influence on the phenotype. DNA in the genome is only one aspect of the complex mechanism that keeps an organism running &ndash; so decoding the DNA is one step towards understanding the process. However, by itself, it does not specify everything that happens within the organism. The basic flow of genetic information in a cell is as follows. The DNA is transcribed or copied into a form known as &ldquo;RNA&rdquo;. The complete set of RNA (also known as its transcriptome) is subject to some editing (cutting and pasting) to become messenger-RNA, which carries information to the ribosome, the protein factory of the cell, which then translates the message into protein.</p> <p>&nbsp;<strong>omics</strong>&nbsp;informally refers to a field of study in biology&nbsp;ending in&nbsp;<em>-omics</em>, such as genomics, proteomics or metabolomics. It reflects the change in orientation towards the quantitative analysis of complete or near-complete assortment of all the constituents of a system. Functional genomics aims at identifying the functions of as many genes as possible of a given organism.&nbsp;&nbsp;It combines different -omics techniques such as transcriptomics and proteomics with saturated mutant collections.Omics</p>
<p>Many &ldquo;omes&rdquo; beyond the original genome&nbsp;have become useful and have been widely adopted by research scientists. Proteomics&nbsp;has become well-established as a term for studying proteins&nbsp;at a large scale.Sangin Kim</p>
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<p>Proteomics</p> <p>Proteins are responsible for an endless number Genomics refers to the study of tasks within the cell. The complete set of proteins genome in a cell can be referred contrast to genetics which refers to as its proteome and the study of protein structure genes and function and what every protein their roles in inheritance. Genomics can be considered a discipline in the cell is doing is known as proteomicsgenetics. The proteome is highly dynamic It applies recombinant DNA, DNA sequencing methods, and it changes from time bioinformatics to time in response to different environmental stimulisequence, assemble, and analyze the function and structure of genomes. The goal of proteomics is field includes efforts to understand how determine the structure entire DNA sequence of organisms and function fine-scale genetic mapping. The field also includes studies of proteins allow them to do what they dointragenomic phenomena such as heterosis, what they interact withepistasis, pleiotropy or other interactions between loci and how they contribute to life processesalleles within the genome.</p> <p>An application It is the new science that deals with the discovery and noting of proteomics is known as protein &ldquo;expression profiling&rdquo; where proteins are identified at a certain time all the sequences in an organism as a result the entire genome of the expression to a stimulusparticular organism. Proteomics The genome can also be used to develop defined as the complete set of genes inside a proteincell. Genomics, is, therefore, the study of the genetic make-network map where interaction among proteins can be determined up of organisms. Genomics is an entry point for a particular living systemlooking at the other &lsquo;omics&rsquo; sciences.</p>
<p>Proteomics can also be applied Omics informally refers to map protein modification to determine a field of study in biology ending in -omics, such as genomics, proteomics or metabolomics. It reflects the change in orientation towards the quantitative analysis of complete or near-complete assortment of all the difference between constituents of a wild type and system. Functional genomics aims at identifying the functions of as many genes as possible of a genetically modified given organism. It is also used to study proteincombines different -protein interactions involved in plant defense reactionsomics techniques such as transcriptomics and proteomics with saturated mutant collections.</p>
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<p>Metabolomics</p>
 
<p>Metabolomics is one of the newest &lsquo;omics&rsquo; sciences. The metabolome refers to the complete set of low molecular weight compounds in a sample. These compounds are the substrates and by-products of enzymatic reactions and have a direct effect on the phenotype of the cell. Thus, metabolomics aims at determining a sample&rsquo;s profile of these compounds at a specified time under specific environmental conditions.</p>
<p>Genomics and proteomics have provided extensive information regarding the genotype but convey limited information about phenotype. Low molecular weight compounds are the closest link to phenotype.</p>
<p>References</p>
<p>1.&nbsp;https://en.wikipedia.org/wiki/Genomics</p>
<p>2.&nbsp;https://en.wikipedia.org/wiki/Omics</p>
<p>3.&nbsp;http://www.isaaa.org/resources/publications/pocketk/15/default.asp</p>
<p>4.&nbsp;http://geneticscertificate.stanford.edu/courses/genomics-and-the-other-omics</p> <p>&nbsp;</p> <p>&nbsp;</p>
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