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Bioperl

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<p style="margin: 0.5em 0px; line-height: 17.9200000762939px; color: rgb(37, 37, 37); font-family: sans-serif; font-size: 14px;">[http://bioperl.net Bioperl.net]</p>
<h2 p style="font-weight: normal; margin: 1em 0px 0.25em; overflow: hidden; padding: 5em 0px; borderline-bottom-widthheight: 1px17.9200000762939px; border-bottom-style: solid; border-bottom-color: rgb(17037, 17037, 17037); font-family: 'Linux Libertine', Georgia, Times, sans-serif; line-height: 1.3; background-image: none; background-attachment: initial; backgroundfont-size: initial; background-origin: initial; background-clip: initial; background-position: initial; background-repeat: initial14px;"><span class="mw-headline" id="Background">Background&nbsp;</spanp><span class="mw-editsection" p style="-webkit-user-select: none; font-size: small; margin-left: 1em; vertical-align: baseline0.5em 0px; line-height: 1em; display: inline-block; white-space: nowrap; unicode-bidi: -webkit-isolate; font-family: sans-serif;"><span class="mw-editsection-bracket" style="margin-right: 0px17.9200000762939px; color: rgb(8537, 8537, 8537); marginfont-leftfamily: 0pxsans-serif;">[</span><a href="http://en.wikipedia.org/w/index.php?title=BioPerl&amp;action=edit&amp;section=1" title="Edit section: Background" style="textfont-decoration: none; color: rgb(11, 0, 128); backgroundsize: none14px;">edit</ab><span class="mw-editsection-bracketheadline" styleid="margin-left: 0px; color: rgb(85, 85, 85); margin-right: 0px;Background">]Background</span></spanb></h2p>
<p style="margin: 0.5em 0px; line-height: 17.9200000762939px; color: rgb(37, 37, 37); font-family: sans-serif; font-size: 14px;">BioPerl is an active&nbsp;<a href="http://en.wikipedia.org/wiki/Open_source" title="Open source" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">open source</a>&nbsp;software project supported by the&nbsp;<a href="http://en.wikipedia.org/wiki/Open_Bioinformatics_Foundation" title="Open Bioinformatics Foundation" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Open Bioinformatics Foundation</a>. The first set of Perl codes of Bioperl was created by&nbsp;<a href="http://en.wikipedia.org/wiki/Tim_Hubbard" title="Tim Hubbard" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Tim Hubbard</a>&nbsp;and Jong Bhak<sup class="noprint Inline-Template Template-Fact" style="line-height: 1; font-size: 11.1999998092651px; white-space: nowrap;">[<i><a href="http://en.wikipedia.org/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed" style="text-decoration: none; color: rgb(11, 0, 128); background: none;"><span title="This claim needs references to reliable sources. (February 2014)">citation needed</span></a></i>]</sup>&nbsp;at&nbsp;<a href="http://en.wikipedia.org/wiki/Medical_Research_Council_(United_Kingdom)" title="Medical Research Council (United Kingdom)" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">MRC</a>&nbsp;Centre Cambridge where the first genome sequencing was carried out by Fred Sanger. MRC Centre was one of the hubs and birth places of modern bioinformatics as it had large amount of DNA sequences and 3D protein structures. The name Bioperl was coined jointly by Jong Bhak and&nbsp;<a href="http://en.wikipedia.org/wiki/Steven_E._Brenner" title="Steven E. Brenner" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Steve Brenner</a>&nbsp;in a small room of&nbsp;<a href="http://en.wikipedia.org/wiki/Centre_for_Protein_Engineering" title="Centre for Protein Engineering" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Centre for Protein Engineering</a>&nbsp;(CPE) of MRC Centre where&nbsp;<a href="http://en.wikipedia.org/wiki/Alan_Fersht" title="Alan Fersht" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Alan Fersht</a>&nbsp;was the director. In that small room,&nbsp;<a href="http://en.wikipedia.org/wiki/Cyrus_Chothia" title="Cyrus Chothia" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Cyrus Chothia</a>&nbsp;and Tim Hubbard were working with some of their Ph.D. students and colleagues. Tim Hubbard is an expert Perl programmer and he was using th_lib.pl that contained many useful Perl subroutines for bioinformatics. Jong Bhak, being the first Ph.D. student of Tim Hubbard created jong_lib.pl. Jong merged the two Perl subroutine libraries into Bio.pl. One day in 1995, Steve Brenner, a Ph.D. student of Cyrus Chothia visited the room and started to discuss what they would call the perl library after some lengthy (a few months) debate on whether Perl is superior to C for bioinformatics as Steve Brenner had his own C library for bioinformatics. The two Ph.D. students named the net Perl library for biology Bioperl after going through names such as protein perl, protperl, PerlBio, and so on. Steve Brenner organized a Bioperl session in 1995 at&nbsp;<a href="http://en.wikipedia.org/wiki/Intelligent_Systems_for_Molecular_Biology" title="Intelligent Systems for Molecular Biology" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">ISMB</a>&nbsp;Cambridge although it did not really happen. Bioperl had some users in coming months including Georg Fuellen who organized a training course in Germany. Georg's colleagues and students extended the Bioperl much and this was joined later by other people such as Steve Chervitz who was actively developing Perl codes for his yeast genome DB. The major expansion came when another Cambridge student&nbsp;<a href="http://en.wikipedia.org/wiki/Ewan_Birney" title="Ewan Birney" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Ewan Birney</a>&nbsp;joined the wagon after another lengthy debate on if Perl was superior to C for bioinformatics and Ewan and many other people were very active in developing Bioperl.<sup class="noprint Inline-Template Template-Fact" style="line-height: 1; font-size: 11.1999998092651px; white-space: nowrap;">[<i><a href="http://en.wikipedia.org/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed" style="text-decoration: none; color: rgb(11, 0, 128); background: none;"><span title="This claim needs references to reliable sources. (December 2013)">citation needed</span></a></i>]</sup></p>
<p style="margin: 0.5em 0px; line-height: 17.9200000762939px; color: rgb(37, 37, 37); font-family: sans-serif; font-size: 14px;">The first stable release was on 11 June 2002; the most recent stable (in terms of API) release is 1.6.9 from 14 April 2011. There are also developer releases produced periodically. Version series 1.6.0 is considered to be the most stable (in terms of bugs) version of BioPerl and is recommended for everyday use, but the nightly builds are also extremely stable, and many BioPerl users stay current with those.</p>
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