Changes

<h1><span style="font -size:12px">1. ATAD5&nbsp;ATPase family, AAA domain containing 5 [&nbsp;<em>Homo sapiens</em>&nbsp;(human) ]</span></h1> <p><span style="4font-size:12px">A highly annotated wholeGene ID: 79915, updated on 26-genome sequence of a Korean individual.May-2016</span></p> <p><span style="font-size:12px">&nbsplt;i want to understand about PCNA and ATAD5 role. so pick that&gt;<br /span><br /p>Kim JI, Ju YS, Park H, Kim S, Lee S, Yi JH, Mudge J, Miller NA, Hong D, Bell CJ, Kim HS, Chung IS, Lee WC, Lee JS, Seo SH, Yun JY, Woo HN, Lee H, Suh D, Lee S, Kim HJ, Yavartanoo M, Kwak M, Zheng Y, Lee MK, Park H, Kim JY, Gokcumen O, Mills RE, Zaranek AW, Thakuria J, Wu X, Kim RW, Huntley JJ, Luo S, Schroth GP, Wu TD, Kim H, Yang KS, Park WY, Kim H, Church GM, Lee C, Kingsmore SF, Seo JS<p><span style="font-size:12px">source comes from. http://www.ncbi.nlm.nih. gov/protein/26080431?report=fasta</span><br /p>[1] Genomic Medicine Institute (GMI), Medical Research Center, Seoul National University, Seoul 110<h1>ATPase family AAA domain-799, Korea containing protein 5 [2Homo sapiens] Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, [</h1> <p>NCBI Reference Sequence: NP_079133.3] Macrogen Inc</p> <pre>&gt;gi|26080431|ref|NP_079133., Seoul 1533| ATPase family AAA domain-023, Korea containing protein 5 [4Homo sapiens] Psoma Therapeutics, Inc., Seoul 110-799, Korea [5] These authors contributed equally to this work. MVGVLAMAAAAAPPPVKDCEIEPCKKRKKDDDTSTCKTITKYLSPLGKTRDRVFAPPKPSNILDYFRKTSPTNEKTQLGKECKIKSPESVPVDSNKDCTTPLEMFSNVEFKKKRKRVNLSHQLNNIKTENEAPIEISSDDSKEDYSLNNDFVESSTSVLRYKKQVEVLAENIQDTKSQPNTMTSLQNSKKVNPKQGTTKNDFKKLRKRKCRDVVDLSESLPLAEELNLLKKDGKDTKQMENTTSHANSRDNVTEAAQLNDSIITVSYEEFLKSHKENKVEEIPDSTMSICVPSETVDEIVKSGYISESENSEISQQVRFKTVTVLAQVHPIPPKKTGKIPRIFLKQKQFEMENSLSDPENEQTVQKRKSNVVIQEEELELAVLEAGSSEAVKPKCTLEERQQFMKAFRQPASDALKNGVKKSSDKQKDLNEKCLYEVGRDDNSKKIMENSGIQMVSKNGNLQLHTDKGSFLKEKNKKLKKKNKKTLDTGAIPGKNREGNTQKKETTFFLKEKQYQNRMSLRQRKTEFFKSSTLFNNESLVYEDIANDDLLKVSSLCNNNKLSRKTSIPVKDIKLTQSKAESEASLLNVSTPKSTRRSGRISSTPTTETIRGIDSDDVQDNSQLKASTQKAANLSEKHSLYTAELITVPFDSESPIRMKFTRISTPKKSKKKSNKRSEKSEATDGGFTSQIRKASNTSKNISKAKQLIEKAKALHISRSKVTEEIAIPLRRSSRHQTLPERKKLSETEDSVIIIDSSPTALKHPEKNQKKLQCLNDVLGKKLNTSTKNVPGKMKVAPLFLVRKAQKAADPVPSFDESSQDTSEKSQDCDVQCKAKRDFLMSGLPDLLKRQIAKKAAALDVYNAVSTSFQRVVHVQQKDDGCCLWHLKPPSCPLLTKFKELNTKVIDLSKCGIALGEFSTLNSKLKSGNSAAVFMRTRKEFTEEVRNLLLEEIRWSNPEFSLKKYFPLLLKKQIEHQVLSSECHSKQELEADVSHKETKRKLVEAENSKSKRKKPNEYSKNLEKTNRKSEELSKRNNSSGIKLDSSKDSGTEDMLWTEKYQPQTASELIGNELAIKKLHSWLKDWKRRAELEERQNLKGKRDEKHEDFSGGIDFKGSSDDEEESRLCNTVLITGPTGVGKTAAVYACAQELGFKIFEVNASSQRSGRQILSQLKEATQSHQVDKQGVNSQKPCFFNSYYIGKSPKKISSPKKVVTSPRKVPPPSPKSSGPKRALPPKTLANYFKVSPKPKNNEEIGMLLENNKGIKNSFEQKQITQTKSTNATNSNVKDVGAEEPSRKNATSLILFEEVDVIFDEDAGFLNAIKTFMATTKRPVILTTSDPTFSLMFDGCFEEIKFSTPSLLNVASYLQMICLTENFRTDVKDFVTLLTANTCDIRKSILYLQFWIRSGGGVLEERPLTLYRGNSRNVQLVCSEHGLDNKIYPKNTKKKRVDLPKCDSGCAETLFGLKNIFSPSEDLFSFLKHKITMKEEWHKFIQLLTEFQMRNVDFLYSNLEFILPLPVDTIPETKNFCGPSVTVDASAATKSMNCLARKHSEREQPLKKSQKKKQKKTLVILDDSDLFDTDLDFPDQSISLSSVSSSSNAEESKTGDEESKARDKGNNPETKKSIPCPPKTTAGKKCSALVSHCLNSLSEFMDNMSFLDALLTDVREQNKYGRNDFSWTNGKVTSGLCDEFSLESNDGWTSQSSGELKAAAEALSFTKCSSAISKALETLNSCKKLGRDPTNDLTFYVSQKRNNVYFSQSAANLDNAWKRISVIKSVFSSRSLLYVGNRQASIIEYLPTLRNICKTEKLKEQGKSKRRFLHYFEGIHLDIPKETVNTLAADFP</pre> <p>&nbsp;<br /p> <p>&nbsp;<br /p>Recent advances in sequencing technologies have initiated an era of personal genome sequences. To date, human genome sequences have been reported for individuals with ancestry in three distinct geographical regions<p>result :&nbsp;http: a Yoruba African, two individuals of northwest European origin, and a person from China//zhanglab. Here we provide a highly annotated, whole-genome sequence for a Korean individual, known as AK1ccmb. The genome of AK1 was determined by an exacting, combined approach that included whole-genome shotgun sequencing (27med.8x coverage), targeted bacterial artificial chromosome sequencing, and high-resolution comparative genomic hybridization using custom microarrays featuring more than 24 million probesumich. Alignment to the NCBI reference, a composite of several ethnic clades, disclosed nearly 3.45 million single nucleotide polymorphisms (SNPs), including 10,162 nonedu/I-synonymous SNPs, and 170,202 deletion or insertion polymorphisms (indels)TASSER/output/S274747/</p> <p>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;&nbsp;http://zhanglab. SNP and indel densities were strongly correlated genome-wideccmb. Applying very conservative criteria yielded highly reliable copy number variants for clinical considerationsmed. Potential medical phenotypes were annotated for non-synonymous SNPs, coding domain indels, and structural variantsumich. The integration of several human wholeedu/I-genome sequences derived from several ethnic groups will assist in understanding genetic ancestry, migration patterns and population bottlenecks.&nbsp;TASSER/output/S274747/<br /p> <br /p>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;<a href="http://wwwzhanglab.ccmb.med.natureumich.comedu/natureI-TASSER/journaloutput/vaopS274747/ncurrent/full/nature08211S274747_results.tar.htmlbz2">http://wwwzhanglab.ccmb.med.natureumich.comedu/natureI-TASSER/journaloutput/vaopS274747/ncurrent/full/nature08211S274747_results.tar.htmlbz2</a><br /p>