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Sungbin Lim

1. What is history of life?
2. How does adaption evolve?

quesiton of evolution
1. What is necessary to make a new species?
 - How many genes?
     How much of the genome needs to diverge in order to create a new species?
 - What type of genes?
     What sort of genes/genomic regions are contained within 'highly divergent part of the genome'?
 - Where are they located in the genome?
2. Denovo evolution or standing variation?

3. Pathogen can be clues to detect evolution. Malaria in Human evolution.
  - Malaria study in natural selection.
  - Characterize genomic variation. Search for signals of genome evolution
  - Sequence drug resistance strain. Figure out where are most diverse region. -> 논문 : Variation data reveals drug resistance genes


Conclusion
1. More data+genome sequencing is helping to resolve fundamental questions in evolutionary biology
  - Phylogenetic relationships
  - Evolution of adaptive traits
  - Human evolution/ demography
2. New problems
  - Function of adaptive loci
  - Demographic methods
  - Lots of data


How can 16S RNA sequencing being central method of identifying species in microbiome?