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4. Transcriptomics Class (0603)

558 bytes added, 22:06, 13 June 2016
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<p style="margin-left: 40px">&nbsp;RNA is classified into two categories, coding RNA and non coding RNA. Messenger RNA is included in the coding RNA. It means that they encode amino acid sequences, so they act as template for protein synthesis. It consists of 5&rsquo; cap, 5&rsquo; UTR, coding sequence, 3&rsquo; UTR, Poly-A tail.</p>
 
<p><strong>&nbsp;&nbsp; Relationship between transcriptome and proteome.</strong></p>
 
<p style="margin-left: 40px">&nbsp;As I mentioned before, protein is made from the transcribed mRNA. The final aim of mRNA is to produce protein which changes phenotype, so I think that study of proteome is more efficient way to measure gene expression than study of transcriptome. Half life of RNA is short because it can be easily degraded by environmental change like temperature or pH. As a result, amount of protein is usually not correlated to amount of mRNA.</p>
<p><strong>&nbsp;&nbsp; What is a UTR?</strong></p>
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