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From Biolecture.org
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<h1>Principles of Bioinformatics</h1>
<p> Bioinformatics is a field that invents methods and computer program for understanding biological data. In this days, there are many programs for analyzing gene expression, protein expression, mapping genes and gene annotation. Due to this many biology field can research conveniently and developed more such as genomics and proteomics.</p>
<h1>Bioprogramming</h1>
<p> Bioprogrmming is a process for making program of bioinformatics.[http://www.fao.org/docrep/s6665e/s6665e03.htm]</p>
<h1>Genomics</h1>
<p> Genomics is discipline of genetics for sequencing, assembling and analyzing the function and structure of entire genomes, not single genes.</p>
<p> Human genome project is a large scale research project. Its aim are defining DNA sequence of human, find genes and mapping genes in gemone. This project is done in 2004 and people found that human has 3 billion nucleotides and 20,500 genes.[https://en.wikipedia.org/wiki/Human_Genome_Project]</p>
<h1>Epigenomics and Phenomics</h1>
<h2h3>Epigenomics</h2h3>
<p> Epigenomics study the epigenetic molecule in a cell, which are DNA methylation, histone modification and RNA interference.</p>
<h3h4>Techniques</h3h4>
<h5>ChIp-chip</h5>
<p> ChIp-chip is a combined technique for chromatin immunoprecipitation and DNA microarray. It can detect interactions between proteins and DNA, especially DNA-binding proteins.[https://en.wikipedia.org/wiki/ChIP-on-chip]</p>
<h5>ChIp-seq</h5>
<p> ChIp-seq is another method for detecting DNA-binding protein sites, which is combination of chromatin immunoprecipitation and DNA sequencing.[https://en.wikipedia.org/wiki/ChIP-sequencing]</p>
<h5>Bisulfite sequencing</h5>
<p> Bisulfite sequencing is a technique for detecting DNA methylation pattern. The idea is coming from that bisulfite can change cytosine to uracil but can't change 5-methylcystosine. So by compairing orginal DNA and bisulfite-treated DNA, people can find DNA methylation pattern.[https://en.wikipedia.org/wiki/Bisulfite_sequencing]</p>
<h3>Phenomics</h3>
<p> Phenomics study the phenomenon of a organism in respond to gene mutation and environment change.</p>
<h1>Canceromics and Geromics</h1>
<p> Canceromics is a biological field of studying cancer. And geromics is a biological field of studying aging.</p><h1>What Is Real?</h1><p> In case tangible things, real is the thing that all people can see directly. For example, since 63 building is in Seoul and we can go to Seoul and see it, 63 building real. However, since we can't see alien anywhere, alien is not real. If all the people can see alien directly, then alien changes real. In case of formless thing, such as past people and event, if so many articles state and explain something, then that is considered real. In other words, reality is not absolute concept. Reality can be change relatively.</p>
